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Form der ArbeitRoche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche, where every voice matters.
The Position
Principal Scientist / Senior Principal Scientist
This position is part of the Pharmaceutical Research and Development organization. Within Pharmaceutical Research and Development, we transform molecules to medicines by designing and delivering customized clinical formulations and developing robust commercial drug products that benefit patients.
As a Principal Scientist/ Senior Principal Scientist in Drug Product Development, you are responsible for developing robust formulations and lean manufacturing processes for oral dosage forms of new chemical entities. Furthermore, you are driving scientific initiatives, and supporting the department in defining the scientific strategy to assure the scientific excellence in Pharmaceutical R&D. In this position, you work closely in international teams together with scientists and management from other disciplines (chemistry, analytics, quality, regulatory and commercial production) and you represent the department in technical development teams (CMC) and scientific boards.
In this role, you will:
Develop robust formulations and manufacturing processes for oral solid drug products, utilizing various technologies to facilitate successful process validation at commercial sites.
Drive scientific excellence within Pharmaceutical R&D by implementing new and innovative manufacturing technologies, integrating relevant trends and concepts into the department's strategy.
Inspire and influence scientific teams at Roche and external partners, fostering collaboration with international scientific consortia.
Contribute to authoring and reviewing technical reports, manufacturing instructions, process validation documents, and regulatory submissions to support licensing.
Actively protect the intellectual property values of our diverse range of Roche products.
As a candidate, you:
Bring a PhD in Pharmaceutical Technology or a Master's degree in Pharmaceutical Technology, with a background in chemical/process engineering or material science or a related discipline. Additionally, you have over 10 years of industrial experience in drug product development.
Demonstrate a broad experience in drug product development for oral dosage forms, including authoring CMC sections of regulatory dossiers, interacting with health authorities, and a strong familiarity with GMP/Compliance requirements.
Ideally, possess experience in developing complex drug delivery technologies, such as special technologies for pediatric and geriatric patient populations, and working in close collaboration with external CMO/CLOs.
Display high motivation and the ability to work collaboratively as well as independently, with a proven track record of driving results and implementing innovative solutions.
Embrace openness and flexibility to change, along with "out of the box" thinking skills. Additionally, you have excellent communication abilities, a coaching mindset, and strong team player skills.
Who we are
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we’ve become one of the world’s leading research-focused healthcare groups. Our success is built on innovation, curiosity and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites. Read more.
Besides extensive development and training opportunities, we offer flexible working options, 18 weeks of maternity leave and 10 weeks of gender independent partnership leave. Our employees also benefit from multiple services on site such as child-care facilities, medical services, restaurants and cafeterias, as well as various employee events.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.
